How many times would it be appropiate to contact an employer to see if they had made a decision to hire or not

I went for an interview last Tuesday on a job that I really liked. After the interview the hiring manager said I should hear something by Friday or early next week. So far I haven't heard anything yet. I left a voicemail on Monday with the recruiter to see if a decision has been made. Still no reply. I sent the hiring manager a thank you email on Tuesday to see if a decision has been made. Still no reply. Should I give up or keep trying to see if a decision has been made? And how many attempts would seem inappropiate?